Cells

A goal of the Knight ADRC Biomarker Core is to collect, characterize, and bank fibroblasts and iPSC from deeply phenotyped research participants to be made available to researchers who are performing studies related to dementia, aging, and other neurodegenerative disorders. 

You can access our fibroblast/iPSC request form HERE.

For additional questions on how to access our cell line repository, please contact Celeste Karch at karchc@wustl.edu or Jacob Marsh at jacobmarsh@wustl.edu

Dominantly Inherited Alzheimer’s Network

To learn more about the Dominantly Inherited Alzheimer’s Network, please visit the DIAN homepage. To request resources please visit the DIAN Resource Page.

The Dominantly Inherited Alzheimer’s Network (DIAN) collects data related to Alzheimer’s disease through biomarker and genetic analysis, neural imaging, and clinical and cognitive data. The image depicts the following:
1. A human form labeled “clinical and cognitive” and showing the neural network;
2. A brain scan labeled “imaging” and listing the scanning procedures “Amyloid PET, Tau PET and MRI;”
3. Colored specimen collection tubes labeled CSF and plasma
4. Diagram of a skin biopsy, and immunocytochemistry stained images of the resulting Fibroblasts and iPSCs
5. A DNA double helix and web of connected dots to illustrate Genetic analysis through sequencing, WGS, epigenomics, transcriptomics, proteomics, lipidomics, and metabolomics.
The Dominantly Inherited Alzheimer’s Network (DIAN) collects data related to Alzheimer’s disease through biomarker and genetic analysis, neural imaging, and clinical and cognitive data

Knight Alzheimer’s Disease Research Center

To learn more about the Knight Alzheimer’s Disease Research Center, please visit the Knight ADRC homepage. To request resources please visit the Knight ADRC Resource Page.